This report identifies strategic development opportunities to leverage higher utilization of the transportation capabilities of the ADHS, rail, water, and air transportation systems in the Appalachian Region through regional intermodal transportation facilities. The study assesses how transportation reliability and congestion at key freight consolidation nodes of national trade gateways could increase the logistics value of the ADHS and potential intermodal sites in Appalachia, including inland ports. The report provides transportation and economic development planners an assessment of national and regional forecasts of transportation and trade flows for future regional transportation demands.